Human Sera
Cayman Chemical BIlIverdInhydrochlorIde 50mg
A green bile pigment produced from the oxidation of heme in a reaction catalyzed by heme oxygenase and further reduced to bilirubin by biliverdin reductase; possesses anti-mutagenic and antioxidant properties, scavenging free radicals
Cayman Chemical BD 1008hydrobromIde 50mg
A selective antagonist of the σ1 receptor (Ki = 2 nM) that displays 4-fold selectivity for σ1 over σ2; used to modulate signaling through σ receptors by cocaine and in models of learning and memory impairment
Cayman Chemical Sopoa alopcuod Sopoadn 100mg
A quinolizidine alkaloid; reduces viral titers in CVB3-infected primary neonatal rat cardiomyocytes at 1 and 5 UG/ml; inhibits the growth of, and induces apoptosis in, SW480 colorectal cancer cells, as well as reduces tumor growth in an SW480 mouse xenograft model; reduces increases in TNF-α, IL-8, and PGE2 levels in a mouse model of carrageenan-induced paw edema at 12.15 and 48.6 mg/kg
Cayman Chemical 2hydroy MyrIsTC ACD mthy 50mg
A 2-hydroxy form of myristic acid methyl ester; levels decrease to <1% in aquatic microbial communities after administration of Atradex (245 mg/L)
Cayman Chemical Cholesterol a-LInolenate 100mg
A cholesterol ester; found in fatty streaks and atherosclerotic plaques isolated from human aorta
Cayman Chemical 4methylNMethylbuphedron 50mg
A para-methyl analog of buphedrone with an aminomethyl addition; intended for research and forensic applications
Sigma Aldrich Fine Chemicals Biosciences SigMatrix Ultra Serum Dilu
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Cayman Chemical BenIdIpInhydrochlorIde 100mg
An orally bioavailable inhibitor of L-, T-, and N-type calcium channels; IC50 = 2.7 nM in guinea pig ventricular cells; prevents oxidative stress in vitro and in neural stem cells; has antihypertensive effects; competitive antagonist at mineralocorticoid receptors
Cayman Chemical Betamethason 100mg
A synthetic corticosteroid; reduces BALF MMP-2 and MMP-9 activities, TNF-α levels, and neutrophil number in a mouse model of LPS-induced lung injury; prenatal administration improves neonatal lung function but decreases hippocampal and corpus callosum neuron density and induces motor function deficits in a rabbit model of late preterm birth at 0.1 mg/kg; extends gestational length in a rat model of HMGB1-induced preterm labor
Cayman Chemical ButyrylLcarnItInchLRIde 50mg
A butyrate ester of carnitine; blocks carnitine uptake by the carnitine transporter and glycine transport by the amino acid transporter in HRPE cells (IC50s = 1.5 µM and 4.6 mM, respectively)
Cayman Chemical N6-CyclohexyladenosIn 50mg
An adenosine receptor agonist; selectively binds to adenosine A1 receptors in rat cortical membranes (IC50 = 2.3 nM) over A2 receptors in rat striatal membranes (IC50 = 870 nM); decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC25s = 5 and 860 nM, respectively); decreases heart rate and blood pressure in normotensive rats in vivo (EC25s = 2.4 and 4.2 μg/kg, respectively); induces sleep in rats via basal forebrain infusion at 100 μM; decreases locomotor activity in mice (ED50 = 60 μg/kg, i.p.)
Cayman Chemical SItaglIptInphosphate 50mg
A DPP-4 inhibitor (IC50 = 18 nM); selective for DPP-4 over DPP-8 (IC50 = 48 µM) as well as several other peptidases; improves glucose tolerance in insulin-resistant Zucker fatty and high-fat diet fed rats as well as ob/ob and high-fat diet fed mice; reduces hyperglycemia in mice fed a high-fat diet with streptozotocin-induced diabetes
Cayman Chemical LevobetaxololhydroCLOrID 100mg
A β1-adrenergic receptor antagonist (Ki = 0.76 nM for the human receptor); selective for β1-ARs over β2-ARs (Ki = 32.6 nM), as well as a panel of 89 additional receptors (IC50s = >1 µM); inhibits isoproterenol-induced cAMP production in human non-pigmented ciliary epithelial cells (Ki = 16.4 nM); topical application reduces intraocular pressure in a cynomolgus monkey model of ocular hypertension at 150 UG/eye
Cayman Chemical StramustIn PhosphatSodIu 100mg
A derivative of estradiol that destabilizes microtubules (Kds = 10 and 15 µM for MAP-1 and MAP-2, respectively); induces cell cycle arrest in mitosis at the metaphase stage in DU145 and PC3 prostate cancer cells; induces apoptosis in U87MG human malignant glioma cells