Human Sera
Cayman Chemical NNItrosoNmethyl4AmInobut 50mg
A nitrosamine carcinogen; oxidized to MOPN in isolated rat liver mitochondria; induces bladder transitional cell carcinomas in rats at 300 mg/L per day in the drinking water
Cayman Chemical 5-DeoxyadenosIn 50mg
An adenosine analog; an intermediate in the degradation of S-adenosyl-L-methionine; has been used in the study of enzyme kinetics, including those of phosphomethylpyrimidine synthase, glutamate mutase, and 5’-methylthioadenosine phosphorylase
Cayman Chemical 1Stearoyl2MyrIstoylsngly 50mg
An asymmetric phospholipid that can interdigitate with equal length (symmetric) acyl chain phospholipids in bilayer membranes to potentially minimize the hydrophobic mismatch between acyl chains
Cayman Chemical 2 5-nhydro-D-mnItol 50mg
An antimetabolic fructose analogue that increases food intake in rats
Cayman Chemical NaloxonazInhydrochlorIde 50mg
A μ-opioid receptor antagonist (Ki = 0.054 nM in a radioligand binding assay); selective for μ-opioid over κ- and δ-opioid receptors (Kis = 11 and 8.6 nM, respectively, in radioligand binding assays); selectively binds to high-affinity µ1-opioid over μ- and δ-opioid receptors (Kds = 0.1, 2, and 5 nM, respectively); reverses sufentanil-induced antinociception, hypercapnia, and hypoxia in rats at 0.16 mg/kg; reduces ethanol self-administration and food intake in rats at 10 mg/kg; inhibits cocaine-induced place preference in rats at 20 mg/kg
Cayman Chemical PInostrobIn 50mg
A flavonoid with diverse biological activities; induces QR in murine hepatoma cells (QR doubling concentration of 500 nM); inhibits TNF-α and IL-1β production in RAW 264.7 macrophages (IC50s = 17.28 and 23.5 μM, respectively) and in LPS-stimulated rats (48.6 and 55% reduction, respectively); shows selective cytotoxicity for CCRF-CEM leukemia cells (IC50 = 10.2 μM) in a panel of eight cancer cell lines (IC50s = >30 μM)
Cayman Chemical GamIthromycIn 50mg
An antibiotic; active against macrolide-resistant R. equi and S. zooepidemicus (MIC90s = 1 and 0.125 μg/ml, respectively); reduces the number of pneumonic lesions in a bovine M. haemolytica challenge model at a dose of 6 mg/kg
Cayman Chemical socorydn 50mg
An aporphine alkaloid; reduces the action potential duration and amplitude in isolated canine Purkinje fibers at 100 µM; induces relaxation of norepinephrine-precontracted isolated rabbit aortic strips (EC50 = 12.6 µM); cytotoxic to A549 lung cancer cells (IC50 = 197.73 µM), as well as Huh7, HepG2, SNU-449, and SNU-387 hepatic cancer cells (IC50s = 161.3, 148, 262.2, and 254.1 UG/ml, respectively); reduces tumor growth in a Huh7 mouse xenograft model when used in combination with doxorubicin
Utak Normal Human Serum, 500mL
100% Real Normal Human Serum is collected in FDA-licensed facilities within the United States from healthy adult donors. The Normal Human Serum is screened for common drugs of abuse and alcohol. Frozen serum is suitable for all testing methods, including LCMS, LC-MS/MS, GCMS, Time of Flight (TOF), ELISA, EMIT and other immunoassays. This product uses Potassium Oxalate as an anticoagulant and Sodium Fluoride for preservation.
Cayman Chemical NordeoxycholIc AcId 100mg
A metabolite of norcholic acid and derivative of deoxycholic acid; hepatic levels are decreased in rats in a high-fat diet model of NAFLD; serum levels are lower in men compared with women; has commonly been used as an internal standard for the quantification of bile acids in various sample types by GC- and LC-MS
Cayman Chemical AlarelInacetate 100mg
A peptide agonist of GnRH; binds to GnRHR (Kd = 0.2 nM); decreases GnRH and GnRHR expression in the preoptic area and pMBH, respectively, of ovariectomized estradiol-treated rats at 6 ng, i.c.v., indicating an ultrashort negative feedback loop; induces desensitization in the pituitary and decreases serum estradiol levels and ovarian and uterine weight in neonatal and adult female rats; reduces tumor growth in an HEC-1-B mouse xenograft model at 20, 40, and 80 UG/mg
Cayman Chemical AcetylDLcarnItInchlorIde 100mg
A racemic mixture of acetyl-D-carnitine and acetyl-L-carnitine; increases the oxidation rate of the branched-chain 2-oxo acid 3-methyl-2-butanoate in isolated rat muscle mitochondria in the absence of carnitine at 1 mM; decreases the hind limb vasculature blood flow rate in rats; decreases the levels of palmitic acid and oleic acid in the cerebral cortex during the recovery period in a dog model of insulin-induced hypoglycemic brain injury
Cayman Chemical trns-ZeatIn RIbosIde 100mg
A cytokinin; suppresses hypocotyl adventitious root formation in cucumber plants from 0.001-1 µM; increases the activity of SOD, APX, CAT, and POD in the leaves, as well as improves turf quality and delays leaf wilting in a creeping bentgrass model of drought stress at 10 µM